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| Management number | 204569903 | Release Date | 2025/10/14 | List Price | $11.39 | Model Number | 204569903 | ||
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Senergy Topical Solution for Dogs 20.1–40 lbs is a monthly, prescription-strength parasiticide formulated to protect medium-sized dogs against fleas, heartworms, ear mites, mange, and American dog ticks. The active ingredient, Selamectin, is a broad-spectrum antiparasitic and endectocide that works transdermally to control internal and external parasites. Senergy is a reliable alternative to Revolution for Dogs and offers the same core protection at a more budget-friendly price.
Whether your dog spends time outdoors, at the park, or around other pets, this topical solution helps safeguard their health with one easy, once-a-month application.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial.
Ensure your pet receives the proper protection by selecting the right size of Senergy Topical Solution based on their weight. Explore all available weight-specific options:
Each formulation delivers the same trusted protection against fleas, heartworms, ear mites, and more—sized just right for your pet's weight and age.
Senergy offers 6-in-1 parasite protection tailored to the needs of medium-breed dogs. Here’s how it exceeds expectations compared to competitor brands:
Kills adult fleas and prevents flea eggs from hatching for one full month
Prevents heartworm disease caused by Dirofilaria immitis
Treats and controls ear mites (Otodectes cynotis)
Treats sarcoptic mange (Sarcoptes scabiei) infections
Kills American dog ticks (Dermacentor variabilis)
Water-resistant after 2 hours of application
Vet-recommended with proven bioavailability and safety profile
Alternative to Revolution at lower cost
Senergy's primary ingredient, Selamectin, is absorbed through the skin and distributed systemically via the bloodstream. It targets the nervous system of parasites, causing paralysis and death. This mechanism makes it effective against both internal parasites (like heartworms) and external parasites (like fleas and mites).
| Parasite Type | Controlled By Selamectin |
|---|---|
| Fleas (Ctenocephalides felis) | ✔️ Kills adults & prevents eggs |
| Heartworms (Dirofilaria immitis) | ✔️ Prevents infestation |
| Ear Mites (Otodectes cynotis) | ✔️ Treats and controls |
| Sarcoptic Mange Mites (Sarcoptes scabiei) | ✔️ Treats infections |
| American Dog Ticks (Dermacentor variabilis) | ✔️ Kills adult ticks |
Always consult your veterinarian for exact dosage instructions depending on your pet's condition.
Use only on dogs weighing 20.1 to 40 lbs and at least 6 weeks of age
Apply one full unit-dose tube topically once a month
Part the hair at the base of the neck and apply the entire contents directly to the skin
Do not massage or spread by hand
Avoid bathing or swimming within 2 hours of application
Each unit dose tube of Senergy Topical Solution contains:
| Ingredient | Function |
|---|---|
| Selamectin | Broad-spectrum antiparasitic; treats internal and external parasites |
Selamectin belongs to the macrocyclic lactone class of antiparasitic agents. It binds to glutamate-gated chloride channels in nerve and muscle cells of parasites, disrupting neural signals and causing paralysis and death.
While generally well-tolerated, some dogs may experience mild and temporary side effects:
Itching or hair loss at application site
Digestive upset (vomiting or diarrhea)
Lethargy
Drooling (if ingested accidentally)
Seek veterinary attention if symptoms persist or worsen.
Not for use in puppies under 6 weeks of age
Do not use on sick, debilitated, or underweight dogs
Avoid contact with human skin and wash hands after application
Keep out of reach of children and other pets until dry
Safe for breeding, pregnant, and lactating dogs as per veterinary guidance
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